ELFT HÍRADÓ

[Zoltan Mate <mate AT namafia.atomki.hu>]

Az MTA Atommagkutató Intézetének nagy előadójában
(Debrecen, Bem tér 18/c. 12. ép. III. em.)
2009. november 12-én, csütörtökön 14:00-kor(!)

                  S. M. Qaim
     (Forschungszentrum Jülich GmbH, Germany) 
  
               Present and Future
   of Medical Radionuclide Production at Cyclotrons  

címmel előadást tart.
Az előadás előtt 13:30-tól tea.
Vendégeket szívesen látunk.

                                        Máté Zoltán


Abstract:

Radionuclide production technology utilizing cyclotrons as irradiation 
sources is well established. Neutron deficient radionuclides in general 
and short-lived positron emitters in particular, are conveniently produced 
at cyclotrons. Those radionuclides are of great value in diagnostic 
nuclear medicine involving emission tomography, i.e. Single Photon 
Emission Tomography (SPECT) or Positron Emission Tomography (PET). In this 
review the status of production of some commonly used SPECT radionuclides, 
e.g. 123I (T˝ = 13.2 h) , 201Tl (T˝ = 73.1 h) etc., as well as standard 
short-lived PET radionuclides, e.g. 11C (T˝ = 20.3 min), 18F (T˝ = 110 
min) etc., will be briefly discussed. The areas needing some further 
development will be outlined. 

Besides routine production of radionuclides at a cyclotron, constant 
efforts are underway in many laboratories to develop new radionuclides for 
further future applications. The work involves fundamental investigations 
on nuclear reactions as well as radiochemical and technological studies 
related to optimisation of production processes. In recent years, 
considerable attention has been devoted to non-standard longer-lived 
positron emitters as well as to low-energy electron and X-ray emitters, 
the former to study slow biokinetics via PET and the latter for internal 
radiotherapy. A brief review of production routes of some interesting 
novel positron emitters, like 64Cu (T˝ = 12.7 h), 73Se (T˝ = 7.1 h), 76Br 
(T˝ = 16.0 h), 86Y (T˝ = 14.7 h), 124I (T˝ = 4.2 d), etc., and therapy 
related radionuclides, like 67Cu (T˝ = 61.9 h), 103Pd (T˝ = 17.0 d), 
193mPt (T˝ = 4.3 d) etc., will be given. Some expected future developments 
will be outlined and the increasing significance of high-intensity 
intermediate energy accelerators will be discussed.
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