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[Fizinfo] EK MFA szeminárium, Kásás Sándor, 2023 február 2, csütörtök 10 óra

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  • From: Horváth Zsolt Endre <horvath.zsolt.endre AT>
  • To: energiausers AT, wignerusers AT, fizinfo AT
  • Subject: [Fizinfo] EK MFA szeminárium, Kásás Sándor, 2023 február 2, csütörtök 10 óra
  • Date: Thu, 26 Jan 2023 07:38:54 +0100
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Kedves Kollégák!

Figyelem, a szokásostól eltérő időpont!!!

2023 február 2-án, csütörtökön 10 órakor az MFA tanácstermében (KFKI 26. épület 1. emelet) kerül sor

Kásás Sándor
(Laboratoire de Physique de la Matière Vivante, EPFL, CH-1015 Lausanne, Switzerland és
Unité Facultaire d’Anatomie et de Morphologie, CUMRL, Université de Lausanne, Switzerland)

Nanomotion based antibiotic sensitivity test

c. előadására.


Fiveyears ago we noticed that attaching living organisms onto an atomic force microscope (AFM) cantilever permits to detect oscillations that can be used to assess the organism metabolic state or its life-death transitions in a label free manner. The technique relies on the fact that all living organisms oscillate at a nanometric scale as long they are alive and stop these movements as soon they die. The oscillations are easily detected with commercially available AFMs or with homemade dedicated instruments. Typical experiment consist in attaching the organism of interest onto an AFM cantilevers and inserting it into the analysis chamber of the instrument. A dedicated electronics monitors the oscillations of the lever for about 15 minutes and eventually a drug that modifies the organism’s metabolism is injected into the analysis chamber. The modifications occurring in the oscillation pattern before and after the injection assess the action of the drug. We successfully tested the technique on bacteria, yeast, vegetal and animal cells. We are therefore confident that AFM based nanomotion detection offers novel avenues to explore living organisms in a label free and chemistry independent manner. During the presentation, numerous examples of nanomotion detection will be presented and the potential applications of the technique in microbiology, medicine and astrobiology will be discussed.

A szemináriumon minden érdeklődőt szívesen látunk!

Horváth Zsolt Endre
Szeminárium koordinátor

Dr. Zsolt E. HORVÁTH
Institute for Technical Physics and Materials Science,
Centre for Energy Research
Hungarian Academy of Sciences
Konkoly Thege Rd. 29-33, 1121 Budapest,
Mail: P.O.Box 49, H-1525 Budapest, Hungary
Phone: +36-1-392-2680, Fax: +36-1-392-2226
e-mail:horvath.zsolt.endre AT
<mailto:horvath.zsolt.endre AT>

  • [Fizinfo] EK MFA szeminárium, Kásás Sándor, 2023 február 2, csütörtök 10 óra, Horváth Zsolt Endre, 01/26/2023

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