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[Fizinfo] DE Szilardtest Fizika Tanszek, Szeminarium

Chronological Thread 
  • From: Erdelyi Zoltan <zerdelyi AT>
  • To: fizinfo <fizinfo AT>
  • Subject: [Fizinfo] DE Szilardtest Fizika Tanszek, Szeminarium
  • Date: Tue, 15 May 2007 12:21:27 +0200 (CEST)
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  • List-id: "ELFT H&#205;RAD&#211;" <>


Debreceni Egyetem
Szilardtest Fizika Tanszek


2007. majus 21., hetfo, 11:00 ora

Debrecen, Bem ter 18/b.
Szilardtest Fizika Tanszek
Eloado terem


Colloid-chemical background of nanotechnologies in medicine

Prof. Zoya Ulberg

Director of

Institute of Biocolloid Chemistry
Ukrainian Academy of Sciences, Kiev

The colloid-chemical aspects of accumulation of gold and silver nanoparticles on the surface of microorganism cells, including cancer and inflamed cells, has been developed. The affinity of metals to live cells is established, and the role of particle's size in the process is cleared. The basis of the phenomenon comprises different colloid-chemical and biochemical processes like diffusiophoresis of particles to the cell, interaction of its double layers and modification of the transmembrane potential, and on the last stage- energy-dependent accumulation and transmembrane transportation of metal into the cell. The mechanisms of these processes as well as the way of their handling are elucidated.

The second direction of our studies was obtaining of nanosized metals (Au, Ag, Fe, Cu, Pt) in cellular structures which play the role of natural templates or nanosize reactors with dimensions up to 10 nm. Biopolymers (exopolysaccharides) excreted by cells have been used as reducing agents and stabilisers of metal's nano- and microcrystals. The opportunity of metal-cell systems to form mesenchymal stem cells is shown. The system consists of hydrogel nanoreactor matrixes (cell size 4-10 nm) that contain therapeutic doses of metals and that are biocompatible with stem cells synthesised in our institute. The nanometal-cell systems have been clinically tested for treatment of different diseases.


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